an electrode immobilized in a graphite matrix with ion pair complex for the determination of diclofenac in pharmaceuticals
نویسندگان
چکیده
a simple, precise, rapid and low-cost potentiometric method for diclofenac determination in pharmaceuticals is proposed. a new diclofenac-sensitive electrode was constructed by incorporating the diclofenac ion pair complex with butyl rhodamine b into graphite matrix. the electrode exhibited a linear response over the concentration range of 1 × 10-4 – 5 × 10-2 mol l-1, a detection limit of 3.9×10-5 mol l-1 with a nernstian slope of 61 ± 2 mv decade-1. the working ph range is 6-11. the electrode is easily constructed, has fast response time (3-11 s) and can be used for the period of six months without any considerable deterioration. the proposed sensor displays good sensitivity for diclofenac in the presence of several substances. it was used to assay diclofenac in pharmaceuticals.
منابع مشابه
An electrode immobilized in a graphite matrix with ion pair complex for the determination of diclofenac in pharmaceuticals
A simple, precise, rapid and low-cost potentiometric method for diclofenac determination in pharmaceuticals is proposed. A new diclofenac-sensitive electrode was constructed by incorporating the diclofenac ion pair complex with butyl rhodamine B into graphite matrix. The electrode exhibited a linear response over the concentration range of 1 × 10-4 – 5 × 10-2 mol L-1, a detection limit of 3.9×1...
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چکیده ندارد.
15 صفحه اولSpectrophotometric Methods for Determination of Sunitinib in Pharmaceutical Dosage Forms Based on Ion-pair Complex Formation
Three rapid spectrophotometric methods were developed for the determination of sunitinib based on the formation of ion-pair complex in acidic medium with bromocresol purple, bromothymol blue, and bromophenol blue. The formed ion-pair complexes, extractable with chloroform, were measured at 422 nm for bromocresol purple, 425 nm for bromothymol blue and 427 nm for bromophenol blue. All these meth...
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عنوان ژورنال:
journal of the iranian chemical researchجلد ۱، شماره ۱، صفحات ۲۵-۳۲
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